Annals of Military and Health Sciences Research

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The Effect of Four Weeks of Vitamin C Supplementation on the Total Antioxidant Capacity and Serum Lactate of Women Active After Eccentric Exercise

Fatemeh Ahmadi 1 , 2 , *
Author Information
1 Master of Exercise Physiology, Payam Noor University, Hamadan, Iran
2 PhD Student, University of Mohaghegh Ardabili, Ardabil, Iran
Article information
  • Annals of Military and Health Sciences Research: December 2016, 14 (4); e59399
  • Published Online: December 31, 2016
  • Article Type: Research Article
  • Received: September 30, 2016
  • Revised: November 7, 2016
  • Accepted: December 13, 2016
  • DOI: 10.5812/amh.59399

To Cite: Ahmadi F. The Effect of Four Weeks of Vitamin C Supplementation on the Total Antioxidant Capacity and Serum Lactate of Women Active After Eccentric Exercise, Ann Mil Health Sci Res. 2016 ; 14(4):e59399. doi: 10.5812/amh.59399.

Copyright © 2016, Annals of Military and Health Sciences Research. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Methods
3. Results
4. Discussion
  • 1. Edge J, Bishop D, Goodman C. The effects of training intensity on muscle buffer capacity in females. Eur J Appl Physiol. 2006; 96(1): 97-105[DOI][PubMed]
  • 2. Helgerud J, Hoydal K, Wang E, Karlsen T, Berg P, Bjerkaas M, et al. Aerobic high-intensity intervals improve VO2max more than moderate training. Med Sci Sports Exerc. 2007; 39(4): 665-71[DOI][PubMed]
  • 3. Wray DW, Nishiyama SK, Monnet A, Wary C, Duteil SS, Carlier PG, et al. Antioxidants and aging: NMR-based evidence of improved skeletal muscle perfusion and energetics. Am J Physiol Heart Circ Physiol. 2009; 297(5)-5[DOI][PubMed]
  • 4. Wadley GD, McConell GK. High-dose antioxidant vitamin C supplementation does not prevent acute exercise-induced increases in markers of skeletal muscle mitochondrial biogenesis in rats. J Appl Physiol (1985). 2010; 108(6): 1719-26[DOI][PubMed]
  • 5. Sacheck JM, Milbury PE, Cannon JG, Roubenoff R, Blumberg JB. Effect of vitamin E and eccentric exercise on selected biomarkers of oxidative stress in young and elderly men. Free Radic Biol Med. 2003; 34(12): 1575-88[DOI][PubMed]
  • 6. Thompson D, Williams C, McGregor SJ, Nicholas CW, McArdle F, Jackson MJ, et al. Prolonged vitamin C supplementation and recovery from demanding exercise. Int J Sport Nutr Exerc Metab. 2001; 11(4): 466-81[PubMed]
  • 7. Benzie IFF, Strain JJ. [2] Ferric reducing/antioxidant power assay: Direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration. 1999; 299: 15-27[DOI]
  • 8. Nikolaidis MG, Kerksick CM, Lamprecht M, McAnulty SR. Does vitamin C and E supplementation impair the favorable adaptations of regular exercise? Oxid Med Cell Longev. 2012; 2012: 707941[DOI][PubMed]
  • 9. Gomez-Cabrera MC, Domenech E, Romagnoli M, Arduini A, Borras C, Pallardo FV, et al. Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance. Am J Clin Nutr. 2008; 87(1): 142-9[PubMed]
  • 10. Oberbach A, Kirsch K, Lehmann S, Schlichting N, Fasshauer M, Zarse K, et al. Serum vaspin concentrations are decreased after exercise-induced oxidative stress. Obes Facts. 2010; 3(5): 328-31[DOI][PubMed]
  • 11. Kang JH, Cook NR, Manson JE, Buring JE, Albert CM, Grodstein F. Vitamin E, vitamin C, beta carotene, and cognitive function among women with or at risk of cardiovascular disease: The Women's Antioxidant and Cardiovascular Study. Circulation. 2009; 119(21): 2772-80[DOI][PubMed]
  • 12. Evans WJ. Vitamin E, vitamin C, and exercise. Am J Clin Nutr. 2000; 72(2 Suppl): 647S-52S[PubMed]
  • 13. Ristow M, Zarse K, Oberbach A, Kloting N, Birringer M, Kiehntopf M, et al. Antioxidants prevent health-promoting effects of physical exercise in humans. Proc Natl Acad Sci U S A. 2009; 106(21): 8665-70[DOI][PubMed]
  • 14. Rosa EF, Ribeiro RF, Pereira FM, Freymuller E, Aboulafia J, Nouailhetas VL. Vitamin C and E supplementation prevents mitochondrial damage of ileum myocytes caused by intense and exhaustive exercise training. J Appl Physiol (1985). 2009; 107(5): 1532-8[DOI][PubMed]
  • 15. Coskun S, Gonul B, Guzel NA, Balabanli B. The effects of vitamin C supplementation on oxidative stress and antioxidant content in the brains of chronically exercised rats. Mol Cell Biochem. 2005; 280(1-2): 135-8[DOI][PubMed]
  • 16. Estegamati A, Zaban A, Dosti. M. . Evaluation of antioxidant status and oxidative stress markers in patients with type II diabetes Melitos [In Persian]. J Endocrin Metab. 2000; 3(4): 239
  • 17. Fisher-Wellman K, Bloomer RJ. Acute exercise and oxidative stress: a 30 year history. Dyn Med. 2009; 8: 1[DOI][PubMed]
  • 18. Kyparos A, Sotiriadou S, Mougios V, Cheva A, Barbanis S, Karkavelas G, et al. Effect of 5-day vitamin E supplementation on muscle injury after downhill running in rats. Eur J Appl Physiol. 2011; 111(10): 2557-69[DOI][PubMed]
  • 19. Cobley JN, Marrin K. Vitamin E supplementation does not alter physiological performance at fixed blood lactate concentrations in trained runners. J Sports Med Phys Fitness. 2012; 52(1): 63-70[PubMed]
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