The effects of hydro-alcoholic extracts of aerial components of Teucrium polium on pressure ulcer healing process and Tensile Strength in Wistar Rats

AUTHORS

Yalda Tajadod 1 , * , Fatemeh Fadaie Fathabadi 2 , Yousef Sadeghi 3 , Abbas Piryaei 4 , Abdolmajid Ayatolahi 5 , Masoomeh Dadpay 6 , Soraya Saremi 7 , Maryam Salimi 8

1 Department of Anatomy and Cell Biology, Faculty of Medicine, International Branch of Shahid Beheshti University of Medical Sciences, Tehran, Iran., Andorra

2 Assistant Professor, Department of Anatomy and Cell Biology, Faculty of Medicine, Shahid Beheshti University, Tehran, Iran, Andorra

3 Professor, Department of Anatomy and Cell Biology, Faculty of Medicine, Shahid Beheshti University, Tehran, Iran, Andorra

4 - Assistant Professor, Department of Anatomy and Cell Biology, Faculty of Medicine, Shahid Beheshti University, Tehran, Iran, Andorra

5 - Professor, Department of Pharmacognosy, Faculty of Pharmacy, Shahid Beheshti University, Tehran, Iran., Andorra

6 - Researcher, Department of Pathology, AJA University of Medical Sciences, Tehran, Iran., Andorra

7 Researcher, Department of Pharmacognosy, Faculty of Pharmacy, Shahid Beheshti University, Tehran, Iran., Andorra

8 Researcher, Department of Anatomy and Cell Biology, Faculty of Medical Sciences, Shahid Beheshti University, Tehran, Iran., Andorra

How to Cite: Tajadod Y, Fadaie Fathabadi F , Sadeghi Y , Piryaei A , Ayatolahi A , et al. The effects of hydro-alcoholic extracts of aerial components of Teucrium polium on pressure ulcer healing process and Tensile Strength in Wistar Rats, Ann Mil Health Sci Res. 2013 ; 11(4):e64700.

ARTICLE INFORMATION

Annals of Military and Health Sciences Research: 11 (4); e64700
Published Online: December 05, 2013
Article Type: Original Article
Received: July 29, 2013
Accepted: November 05, 2013

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Abstract

Background: Wound healing represents a dynamic physiological process influenced by many factors. The aim of the present study was to evaluate the effects of hydro-alcoholic extracts of aerial components of Teucrium polium on the tensile strength in rat. Materials and Methods: Twelve Wistar rats were randomly divided into tow equal (n= 6) treatment and control groups.pressure ulcer were made over the dorsal thoracic region according to the shyn model.Animals were treated with topical hydro-alcoholic extracts of aerial components of Teucrium polium twice a day post surgery until complete healing was achieved. Tensiometry were then studied. Results: No significant difference in biomechanical parameters was observed among the ointment containing of extract 1%, vehicle and control groups. Conclusions: This study shows that topical application of Teucrium polium. Aerial components of Teucrium polium did not have any effect on healing of pressure ulcer in an animal model. Further studies are requiring for assessment of other extracts by different solvents of this plant on pressure ulcer wound healing.

Keywords

: Teucrium Alcoholics Pressure Ulcer Wound Healing Rats

© 2013, Annals of Military and Health Sciences Research. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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