Effect of single – dose prophylactic antibiotic in prevention of groin infection after hernioplasty with prolene mesh

AUTHORS

Shahryar Sadeghi 1 , * , Mohammad Hossein Lasghari 2

1 Assistant professor, Surgical Department, Imam Reza Hospital, Facualy of Medicine, AJA University of Medical Sciences, Tehran, Iran., Andorra

2 Assistant professor, Surgical Department, Imam Reza Hospital, Facualy of Medicine, AJA University of Medical Sciences, Tehran, Iran, Andorra

How to Cite: Sadeghi S , Lasghari M H . Effect of single – dose prophylactic antibiotic in prevention of groin infection after hernioplasty with prolene mesh, Ann Mil Health Sci Res. 2013 ; 11(1):e67371.

ARTICLE INFORMATION

Annals of Military and Health Sciences Research: 11 (1); e67371
Published Online: March 03, 2013
Article Type: Original Article
Received: October 31, 2012
Accepted: February 03, 2013

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Abstract

Background: Use of prosthetic material for inguinal hernia repair has been increased dramatically. Although the use of prophylactic antibiotic for open prosthetic inguinal hernia surgery is controversial, the aim of this study was to determine the effect of antibiotic prophylaxis in prevention of groin infection after hernioplasty with prolen mesh.

Material and Methods: In a prospective, randomized, double- blind placebo- controlled clinical trial wound infection rate in 204 patients was evaluated. The patients were underwent primary inguinal hernia repair electively using prolen mesh from September 2008 to December 2010. Age, gender, type and site of hernia was recorded. Infection was evaluated 3 and 10 days after operation. All complications were recorded.

The result was analyzed using mantel hanszel, chi-square and logistic regression.

Results: Superficial surgical site infection detected in 2 cases (2%) from the antibiotic group and 3 cases (2.9%) in placebo group (P=0.5). There was not deep surgical site infection in both groups. Simple drainage and oral antibiotic performed for 5 infected cases.

Conclusions: Preoperative administration of single- dose antibiotic for tension- free iguinal mesh hernioplasty did not markedly decrease risk of wound infection in our study. So we don’t recommend use of antibiotic prophylaxis for tension free mesh hernioplasty

Keywords

Antibiotic Prophylaxis Hernia Inguinal Surgical Mesh Surgical Wound Infection

© 2013, Annals of Military and Health Sciences Research. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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