The synthesis of chitosan / polyethylene nanofibersoxide on chitosan membrane: an applicable model in tissue engineering

AUTHORS

Asgar Emamgholi 1 , gholamreza Kaka 2 , * , Mino Sadri 3 , Seyyed Homayoon Sadraee 4 , Seyyed Hasan Hosseini 5

1 Researcher, MSc in Nano-biotechnology, Neuroscience Research Center and Nano-biotechnology research center, Baqiyatallah University of Medical Sciences, Tehran, Iran, Andorra

2 Assistant Professor, Neuroscience Research Center and Anatomy Department, Baqiyatallah University of Medical Sciences, Tehran, Iran, Andorra

3 Assistant Professor, Biological Technology Research Institue, Malek Ashtar University of Technology, Tehran, Iran, Andorra

4 Associated Professor, Neuroscience Research Center and Anatomy Department, Baqiyatallah University of Medical Sciences, Tehran, Iran, Andorra

5 Researcher, MSc in Nano-biotechnology, Industrial research center, Baqiyatallah University of Medical Sciences, Tehran, Iran, Andorra

How to Cite: Emamgholi A , Kaka G, Sadri M , Sadraee S H , Hosseini S H . The synthesis of chitosan / polyethylene nanofibersoxide on chitosan membrane: an applicable model in tissue engineering, Ann Mil Health Sci Res. 2012 ; 10(4):e67930.

ARTICLE INFORMATION

Annals of Military and Health Sciences Research: 10 (4); e67930
Published Online: December 04, 2012
Article Type: Original Article
Received: July 11, 2012
Accepted: November 11, 2012

Crossmark

CHEKING

READ FULL TEXT
Abstract

Background: Nanofibers as nano-scaffolds are widely used in tissue engineering. . Electrospun is a way to produce these fiberes. In this study, the synthesis of chitosan nanofibers / polyethylene oxide (CS / PEO) on a very thin membrane of CS as a basement membrane has been investigated.

Materials and Methods: For this purpose, composite solutions with volume fractions - density of CS and PEO, respectively, with ratios of 100 to zero (pure chitosan), 90 to 10 and 80 to 20 in Acetic Acid 5/0 M were prepared. Interactions of two polymers on each other were studied by Fourier transform infra-red spectroscopy (FTIR). Nanofiber diameter and size were studied with Scanning Electron Microscope (SEM). CS membrane polymer solution on the interval the electric field kv 20-18 cm 15-10 and feed rate ml / h 5/0 was electrospun. Nanofiber diameter and size were studied by Scanning Electron Microscope (SEM).

Results: FTIR study of the composite CS / PEO ratio of 20/80 and 10/90 peak tensile bond hydroxyl (OH) and (C = O) chitosan showed in certain areas. Scanning Electron Microscopic images showed that pure CS could not produce nanofibers on any ratios, and they appeared as a droplet. Whereas, nanofibers were created with ratios 80 to 20 and 90 to 10 of CS / PEO composite both on the aluminum foils and thin membrane of CS.

Conclusion: It seems that high viscosity of pure CS prevents nanofibers formation. Whereas, homogeneous nanofibers obtained from the composite of CS / PEO with the ratios 80 to 20, 90 to 10 and pure CS on thin membrane of CS.

Keywords

Nanofibers Electrospinning Chitosan Polyethylene Oxide

© 2012, Annals of Military and Health Sciences Research. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Fulltext

Full text is available in PDF

References

  • 1.

    References are available in PDF

  • COMMENTS

    LEAVE A COMMENT HERE: